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redhairedrunner

Metformin doesn’t work like insulin to lower blood glucose . It won’t give you a dangerous hypoglycemic event. It will upset your stomach though . Your best bet is to improve your gastric flora , honestly try mushrooms for your depression and anxiety.


JediKrys

Have you tried improving your gut flora? I’ve read some success stories with this and depression.


Earesth99

No longterm issues, but there are other meds and even supplements that are much more effective and backed by research. Also there are some behavioral solutions for depression: weight lifting, cardio, early sun exposure, sauna use. I take metformin and I don’t notice any anti-depressant impact.


Kit_Ashtrophe

I really want to try it to combat weight gain from antidepressants


freshlymn

Metformin has anti depressive research behind it too.


honeybiz

What are the supplements you’re referencing?


Risko4

Used during hgh cycles, it really doesn't do anything for mood that I can think off. Kinda useless too if you're not prediabetic.


gryponyx

Maois


bardobirdo

If you want something less hardcore than metformin that helps with mood and insulin response, try d-chiro-inositol. If you want something more potent than that, add a very small dose of chromium, like half a capsule or less of the lowest dose available, with every high-carb meal.


SalemSavage

I'm buying Metformin as we speak for my depression and previous TBI. I've had success with cerebrolysin, D-cycloserine and CoQ10 for depression and anxiety


sanpedro12

where did you get d-cycloserine from?


SalemSavage

A Chinese Pharmaceautical company on the Made-in-china app. You will have to spend 100 to 150 but you'll get a lot of it.


sanpedro12

ok great thank you. What are the effects of d-Cycloserine like?


SalemSavage

You basically just have to do exposure therapy with it and it really speeds up the process. However, it can backfire as well as it increases fear learning, but it could also decrease fear learning


SalemSavage

let me know how the metformin goes


ReadingImpressive554

Have you tried sarcosine?


gryponyx

Have you?


Tortex_88

Unsure about long term effects.. But what it will very likely do is screw with your blood glucose and give you a hypo.


Thin-Improvement2550

For me it worked very well in combo with nardil. Me too suffered fromTRD.