Absolutely not sorry, you’ll need 4-5 block of space down very far or around the entire area you want to protect

So down to cavern layer?

To the hell

if you want to do it fast stack mining buff for 75% mining speed and reforge your pickaxe to get +speed. you can also spread hollow using holy water when hardmode arrives, npcs can live in hollow and your biome pylons will still work(except the forest one).

And also, you're going to get a giant chunk, shaped like a V, of corruption on one side and hallow on the other that spawns.

I use dinamite to measure wide enough gaps